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Captain Carles Puyol will miss Tuesday's Champions League second leg match against London.
The 32-year-old center-back has been sidelined since January due to a knee injury, but it was hoped that he would be able to return for the crucial match against the English team, as he has been training in recent days.
However, doctors have decided that Puyol is not yet ready to return to the field, which will be another headache for coach Pep Guardiola, who is already without the suspended fellow center-back Gerard Pique.
It is speculated that in the heart of the defense, the strategist will trust places to Eric Abidal and Sergio Busquets.
