Victory against "Sevilla" team would guarantee "Juventus" a place in the next stage of the Champions League, but the guests will not be able to compete with the strongest lineup.
The Italian champions traveled to Spain without forward Gonzalo Higuain and defender Medhi Benatia.
The Argentine injured his thigh in Saturday's "Serie A" match against "Pescara," and the Moroccan has not yet recovered.
These losses have been officially confirmed by the "Juventus" team.
The Italians will also be without Paulo Dybala in their lineup, so the nominal forwards will be Mario Mandzukic and 16-year-old Moise Kean.
If the latter player gets his chance, he will become the first player born in this century to play in the tournament.
Our #SFCJuve squad list is in.
Medical updates on @G_Higuain and @MedhiBenatia https://t.co/CK0TyqMbg1 #UCL #FinoAllaFine pic.twitter.com/cktDv0xC8s
— JuventusFC (@juventusfcen) November 21, 2016