On Thursday, in the first leg of the UEFA Europa League round of 16 matches, the tournament favorites Manchester clubs experienced unexpected losses.
In the English Premier League, leaders Manchester City were forced to admit defeat to Lisbon's Sporting with a minimal score of 1-0 in an away match.
The only goal of the match, with a technical shot from the heel at the beginning of the second half, was scored by the home team's center-back Alexandre Luiz Reame.
Manchester United team found themselves in an even worse situation, as they lost 2-3 to the spirited Basques - Bilbao Athletic team in front of their own fans.
The second leg matches will take place next Thursday.
Results:
Lisbon Sporting 1 - 0 Manchester City
51' [1 - 0] A.L.R. Xandao
Kharkiv Metalist 0 - 1 Piraeus Olympiacos
50' [0 - 1] D.F. Torrijos
82' A.L. Edmar was sent off the field ("Metalist")
Enschede Twente 1 - 0 Gelsenkirchen Schalke
61' [1 - 0] L.D. Jong
60' J. Matip was sent off the field ("Schalke")
Liege Standard 2 - 2 Hannover
22' [0 - 1] L. Stindl (from a penalty kick)
27' [1 - 1] Y. Buyens
30' [2 - 1] M. Tchite
56' [2 - 2] M.B. Diouf
Valencia 4 - 2 Eindhoven PSV
11' [1 - 0] V. Ruiz
13' [2 - 0] R. Soldado
43' [3 - 0] R. Soldado (from a penalty kick)
56' [4 - 0] P. Piatti
83' [4 - 1] O. Toivonen (from a penalty kick)
90' [4 - 2] G. Wijnaldum
Alkmaar AZ 2 - 0 Udinese
63' [1 - 0] M. Martens
84' [2 - 0] E. Falkenburg
Madrid Atletico 3 - 1 Istanbul Besiktas
24' [1 - 0] E. Salvio
27' [2 - 0] E. Salvio
37' [3 - 0] Adrian
53' [3 - 1] Simao
Manchester United 2 - 3 Bilbao Athletic
22' [1 - 0] W. Rooney
44' [1 - 1] F. Llorente
72' [1 - 2] O.D. Marcos
90' [1 - 3] I. Muniain
90' [2 - 3] W. Rooney (from a penalty kick)