Club safety Darren Fletcher may not return to the pitch this season. The Scot strained his ankle ligaments last week in the FA Cup match against Reading.
The recovery from the injury will take at least two months, so it is possible that the Scotland national team defender will not return to the field this season, which ends in the second half of May.
"His foot is severely twisted. We have to wait until we can x-ray it later this week. Unfortunately, the news is not good, as the injury is serious and Darren will definitely not play for two months," said club coach Alex Ferguson.
Representing the club for four years, the Scotland national team defender has scored 7 goals in 136 matches.
On Wednesday, the Premier League leaders will play the return Champions League match against the French team Lille, and will suffer more losses. Due to a minor injury, Louis Saha will have to miss the match, and there are doubts about the possibilities of Paul Scholes and Patrice Evra to step onto the field.
Furthermore, last week Ole Gunnar Solskjaer dropped out of the lineup. Due to a minor knee operation, the Norwegian will not be able to play for about a month.