Struggling with player problems, Paris' "Saint Germain" club suffered a second consecutive defeat in the French league on Wednesday.
Thomas Tuchel's team lost 2-3 to the "Nantes" footballers.
The Paris club needed at least one point to secure the champions title, which they could have done already in the past two rounds.
Dani Alves scored for PSG in the 19th minute, but before the end of the first half, the opponents responded with goals - Diego Carlos and Waris Majeed.
D. Carlos increased "Nantes" lead at the beginning of the second half. Towards the end of the match, Metehan Guclu reduced the difference, but it was not enough to save PSG.
With 81 points, PSG leads the closest opponents by a margin of 17 points. There are still six rounds left in the competition.